Tranexamic Acid: What Is It? Benefits for the Skin

GoldSkin > Ingredients > Tranexamic Acid: What Is It? Benefits for the Skin

Tranexamic Acid is a powerful ingredient found in topical skincare products, recognized for its efficacy in treating pigmentation issues and promoting a brighter complexion. But what exactly is Tranexamic Acid? Does this active ingredient really deliver results for the skin? This article will answer these questions and more.

Tranexamic Acid: What Is It?

Tranexamic Acid is an amino acid and a synthetic derivative of lysine, which is soluble in water. Initially, it was primarily used orally to control bleeding and manage trauma-related hemorrhage. It is a safe and effective medication, listed as an essential drug by the World Health Organization (WHO).

Today, Tranexamic Acid is widely applied in various skincare and treatment products. This ingredient can be administered orally, injected, or applied topically to inhibit melanin production, reduce dark spots, and minimize acne scars, resulting in a smoother and brighter complexion. For example, studies have shown that using a 5% concentration of Tranexamic Acid topically can achieve similar results to a 3% concentration of Hydroquinone in treating pigmentation.

Benefits of Tranexamic Acid for the Skin

Reducing Brown Spots and Even Skin Tone

Tranexamic Acid is known for its ability to inhibit melanin production, making it effective in fading brown spots and improving uneven skin tone. For example, a 2019 study demonstrated that participants using Tranexamic Acid for 12 weeks experienced a 27% reduction in pigmentation without any signs of irritation.

Fading Acne Scars

Acne not only damages the skin but also leaves behind red spots. Tranexamic Acid helps diminish these red marks and aids in healing damage caused by both acne and sun exposure. For example, numerous studies have confirmed that Tranexamic Acid significantly improves post-acne skin conditions.

Strengthening the Skin Barrier

The skin barrier plays a crucial role in maintaining hydration and protecting against external factors. Tranexamic Acid can enhance the integrity of the skin barrier. For example, researchers have shown that using a 3% concentration of Tranexamic Acid for two weeks can substantially improve the skin barrier’s function.

Anti-Inflammatory Properties

Tranexamic Acid also possesses anti-inflammatory properties, helping to soothe irritated skin and reduce redness. For example, applying Tranexamic Acid can alleviate damage caused by sun exposure, dirt, or bacteria.

Mechanism of Action of Tranexamic Acid

One of the main causes of pigmentation issues is the increase in melanin-producing cells. Tranexamic Acid works by inhibiting the activity of the enzyme plasmin, which prevents the production of intracellular arachidonic acid, thereby obstructing melanin synthesis. For example, noticeable improvements in pigmentation can typically be seen within 8 to 12 weeks of using Tranexamic Acid.

To optimize the effect of fading pigmentation, it is advisable to combine Tranexamic Acid with Vitamin C or derivatives such as 3-O-Ethyl Ascorbic Acid. These vitamins act as enhancers, allowing Tranexamic Acid to penetrate deeper into the skin and improve discolored areas.

How to Use Tranexamic Acid for Skincare

For Tranexamic Acid to maximize its effectiveness and minimize skin irritation, it is essential to use it correctly. Here are some tips:

Frequency of Use

Tranexamic Acid has been shown to be safe for daily use. However, individuals with sensitive skin or those new to this ingredient should start with a lower frequency, around 1-2 times per week. For example, if no irritation occurs, you can gradually increase usage every other day, eventually transitioning to daily application.

Timing of Use

Experts suggest that Tranexamic Acid can be applied at any time of the day. However, to achieve the best results, it is recommended to use it in your evening skincare routine. For example, ensure that your skin is thoroughly cleansed with an appropriate makeup remover and cleanser before applying Tranexamic Acid.

Combining with Other Actives

Tranexamic Acid can be combined with other active ingredients in your skincare regimen. However, this combination may lead to irritation, particularly for sensitive skin. For example, before mixing Tranexamic Acid with ingredients like Kojic Acid or Phytic Acid, consulting with a dermatologist is advisable.

Concentration of Tranexamic Acid

The concentration of Tranexamic Acid in skincare products should range from 2% to 5%. This concentration is safe for the skin while still being effective in treatment.

Precautions When Using Tranexamic Acid

Tranexamic Acid is an excellent choice for treating hyperpigmentation and achieving a smooth, even complexion. However, there are some important considerations during use:

Patch Test Before Use

Although Tranexamic Acid is suitable for most skin types, it is wise to conduct a patch test on a small area before applying it to your entire face. For example, if there are no adverse reactions after 24 hours, you can safely apply it to the treatment area.

Use Sunscreen

Sun exposure can trigger increased pigmentation, leading to skin darkening. For example, when using Tranexamic Acid, ensure you apply a broad-spectrum sunscreen with an SPF of 30 or higher to protect your skin effectively.

Conclusion

Tranexamic Acid is a crucial ingredient for improving skin conditions, helping to brighten, fade pigmentation, and restore damaged skin. By understanding its benefits and proper usage, you can effectively incorporate Tranexamic Acid into your skincare routine, achieving healthier and more even-toned skin